14 HRT & TRT clinics in Sioux Falls, compared
We verified 14 clinics in Sioux Falls that list hormone therapy on their own website (of 20 verified clinics in the city). Compare them below by the services they name, whether we matched an NPI organization record, telehealth mentions, and the verification date. Terms they use most: Hormone replacement, Hormone therapy, TRT. FDA recommends FDA-approved hormone products and says it lacks evidence that compounded “bioidentical” hormones are safer or more effective. Virtual Care Atlas does not rank or rate clinics; the table is alphabetical. As of .
HRT & TRT clinics in Sioux Falls
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5201 E 57th St, Sioux Falls, SD 57108
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4301 W 57th St #160, Sioux Falls, SD 57108
NPI match · Verified 10/19 -
5617 S Southeastern Ave, Sioux Falls, SD 57108
Verified 10/19 -
4908 E Rosa Parks Pl, Sioux Falls, SD 57110
NPI match · Verified 10/19 -
2001 W Trevi Pl, Sioux Falls, SD 57108
NPI match · Verified 10/19 -
5919 S Remington Pl Ste 200, Sioux Falls, SD 57108
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3800 E Vendavel St, Sioux Falls, SD 57108
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5011 S Louise Ave, Sioux Falls, SD 57108
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2333 W 57th St Ste 102, Sioux Falls, SD 57108
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Sioux Falls, SD 57108
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7208 S Lyncrest Pl, Sioux Falls, SD 57108
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4928 E Rosa Parks Pl, Sioux Falls, SD 57110
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7520 S Grand Arbor Ct Ste 135, Sioux Falls, SD 57108
Verified 10/19 -
5009 S Bur Oak Pl, Sioux Falls, SD 57108
Verified 10/19
No listed clinic here matches every filter you picked. Remove a filter, or check telehealth options.
Compare hormone therapy clinics in Sioux Falls
Facts we verified for each clinic. Order is alphabetical. Virtual Care Atlas does not score or endorse clinics.
| Clinic | Services named | NPI match | Offers telehealth | Verified |
|---|---|---|---|---|
| Accelerate Wellness - Longevity Medicine Clinic | Hormone replacement | — | Yes | |
| Encompass Wellness & Aesthetics | Hormone replacement, Hormone therapy, Testosterone replacement | Yes | Yes | |
| Era Health | Hormone optimization, Hormone replacement, Hormone therapy | — | — | |
| Gameday Men's Health Sioux Falls, SD | Testosterone therapy, TRT | Yes | Yes | |
| Hormones Gone Wild | Hormone therapy | Yes | — | |
| Limitless Male Medical Clinic | Testosterone therapy, TRT | — | — | |
| Liv Med Spa | Sioux Falls, SD | HRT, TRT | — | Yes | |
| LIVE Hydration Spa Sioux Falls | Hormone therapy | — | — | |
| Peakform Wellness Clinic | Hormone replacement | — | Yes | |
| Prairie Roots Health | Hormone therapy | — | — | |
| Prime IV Hydration & Wellness - Sioux Falls | Bioidentical hormones | — | Yes | |
| Radiant Health and Hormone Therapy | Hormone replacement, Hormone therapy, Pellet therapy | — | Yes | |
| Thrive & Co. | Hormone optimization | — | Yes | |
| We Build Champions | Hormone replacement | — | — |
What these clinics call it
Terms found on the 14 clinics' own websites, by number of clinics using each.
| Term on clinic site | Clinics |
|---|---|
| Hormone replacement | 6 |
| Hormone therapy | 6 |
| TRT | 3 |
| Hormone optimization | 2 |
| Testosterone therapy | 2 |
| Bioidentical hormones | 1 |
| HRT | 1 |
| Pellet therapy | 1 |
| Testosterone replacement | 1 |
Also offered by these clinics
- GLP-1 & medical weight loss11 of 14
- Peptide therapy10 of 14
- NAD+ therapy6 of 14
- Sermorelin5 of 14
- Offers telehealth8 of 14
3 of 14 matched to an NPI organization record.
What should I ask a hormone therapy clinic in Sioux Falls before booking?
Clinic websites rarely say who prescribes, where the medication comes from, or what it costs in total. Ask these 4 questions by phone or at the consult. Then check the prescriber's license with the South Dakota medical board or on DocInfo.
- Do you prescribe FDA-approved hormone products, compounded bioidentical hormones, or pellets?
- What baseline and follow-up labs are required, and how often?
- Who is the prescriber, and what is their state license number?
- What's the full cost: consult, labs, medication and any membership?
More in and around Sioux Falls
- All 20 Sioux Falls clinics
- Peptide Therapy in Sioux Falls
- Semaglutide & GLP-1 in Sioux Falls
- NAD+ IV & Injection in Sioux Falls
- Sermorelin in Sioux Falls
- Hormone therapy clinics in South Dakota
- Hormone therapy (HRT / TRT): guide & FDA status
HRT & TRT in Sioux Falls: FAQ
How many clinics offer hormone therapy in Sioux Falls?
14 of the 20 verified clinics in Sioux Falls, SD list hormone therapy on their own website as of October 19, 2026: Accelerate Wellness - Longevity Medicine Clinic, Encompass Wellness & Aesthetics, Era Health, Gameday Men's Health Sioux Falls, SD, Hormones Gone Wild, Limitless Male Medical Clinic, Liv Med Spa | Sioux Falls, SD, LIVE Hydration Spa Sioux Falls and 6 more.
What do Sioux Falls clinics call it on their websites?
The terms we found most often were "Hormone replacement" (6 clinics), "Hormone therapy" (6 clinics), "TRT" (3 clinics), "Hormone optimization" (2 clinics), "Testosterone therapy" (2 clinics). Each clinic's page shows its exact wording and the page we found it on.
Do any Sioux Falls hormone therapy clinics offer telehealth?
8 of these 14 clinics mention telehealth or virtual visits on their website. The prescriber generally needs a license in South Dakota, or wherever you are during the visit.
Is hormone therapy FDA-approved?
FDA recommends FDA-approved hormone products and says it lacks evidence that compounded “bioidentical” hormones are safer or more effective. Our Hormone therapy (HRT / TRT) guide links the FDA sources.
Data year 2026, verified . Virtual Care Atlas doesn’t rate or endorse clinics, and the order is alphabetical. Information comes from each clinic’s public website. Confirm services and prescriber licensing with the clinic. Request a correction.