By Virtual Care Atlas Editorial Team · Updated · Editorial review: Virtual Care Atlas Editorial Team, fact-checked against the cited sources (not a clinical review) · How we verify
What is sermorelin?
Sermorelin is a synthetic peptide that corresponds to the active fragment of growth hormone-releasing hormone (GHRH). Rather than being growth hormone itself, it acts on the pituitary gland, which releases growth hormone.
Sermorelin’s FDA history
According to FDA’s 2013 Federal Register notice:
- GEREF (sermorelin acetate) injection, 0.05 mg/ampule was approved in 1990 for evaluating the pituitary’s ability to secrete growth hormone.
- GEREF 0.5 mg and 1.0 mg vials were approved in 1997 for treating idiopathic growth hormone deficiency in children with growth failure.
- The maker, EMD Serono, discontinued both in 2008.
- In 2013, FDA determined the products were not withdrawn from sale for reasons of safety or effectiveness. That determination allows FDA to approve generic applications if all other requirements are met.
So sermorelin was once an approved drug, but not for the adult “anti-aging” and wellness uses clinics typically promote, and there’s no branded product on the market now. Clinic sermorelin is generally compounded, and FDA’s general statement applies: compounded drugs aren’t FDA-approved, and FDA doesn’t review them for safety, effectiveness or quality before marketing.
Where sermorelin shows up
In our data, clinics that name sermorelin are mostly:
- Men’s health and testosterone clinics.
- Anti-aging and functional medicine practices.
- Peptide-focused clinics and med spas with a medical director.
It’s usually listed next to other peptides, such as ipamorelin and CJC-1295. FDA has flagged those two in its list of bulk substances that may present significant safety risks in compounding. Ask your prescriber exactly which compounds you’d receive.
Questions to ask a sermorelin prescriber
- What evaluation and lab work comes first, and how will you monitor me?
- Which pharmacy compounds it, and is that a 503A pharmacy or a 503B outsourcing facility?
- Is anything else in the preparation? Some clinics offer blends.
- Is there an FDA-approved option for my situation?
- What’s the total cost, itemized, including visits and labs?
How this list is built
We found clinics in public Google Maps listings in each metro and checked each one against its own website on October 19, 2026. A clinic is tagged Sermorelin only if its site names sermorelin. Every listing links to the page where we found it, and shows any NPI Registry match. No ratings, no paid placement. Methodology
Frequently asked questions
Is sermorelin FDA-approved?
Sermorelin acetate was approved as GEREF for treating idiopathic growth hormone deficiency in children with growth failure, and as a diagnostic agent. The maker discontinued those products in 2008. In a 2013 Federal Register notice, FDA determined they were not withdrawn for reasons of safety or effectiveness. Sermorelin prescribed by clinics today for adults, for example for 'anti-aging', is generally compounded and isn't an FDA-approved use.
How does Virtual Care Atlas decide a clinic offers sermorelin?
The clinic's own website must name sermorelin, either more than once or on a page about peptides or sermorelin. We link to where we found it on each listing.
Is sermorelin the same as HGH?
No. Sermorelin is a growth hormone-releasing hormone analog, which acts on the pituitary gland. Human growth hormone (somatropin) is a different molecule. Ask a prescriber to explain the difference and the evidence for your situation.
Do sermorelin clinics also offer other peptides?
Often, yes. Most clinics in this directory that name sermorelin also list peptide therapy, hormone therapy, or both. Use the filter chips on any city page to combine services.
Compounds named on this page: Sermorelin (PubChem CID 16132413).
References
- Determination That GEREF (Sermorelin Acetate) Injection … Were Not Withdrawn From Sale for Reasons of Safety or Effectiveness · Federal Register (FDA notice) (2013)
- Understanding the Risks of Compounded Drugs · U.S. Food and Drug Administration
- Certain Bulk Drug Substances for Use in Compounding that May Present Significant Safety Risks · U.S. Food and Drug Administration (2026)
Before you book
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How to find a legitimate peptide clinicNPI and license lookups, who prescribes, who compounds, and what to ask.
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Is peptide therapy legit?What FDA approval, compounding and a licensed prescriber actually mean.
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How much does peptide therapy cost?Why we do not publish unverified cash prices, and what to ask instead.