Peptide, GLP-1, NAD+ & hormone clinics in Sioux Falls, SD
We verified 20 clinics in Sioux Falls against each clinic's own website. Compare them below by services named, NPI match, telehealth and verification date. As of , the list is: 17 GLP-1 / weight loss, 14 hormone therapy, 11 peptide therapy, 8 NAD+, 5 sermorelin, and 9 mention telehealth. Each listing comes from the clinic’s own website. Filter by service below, then contact the clinic directly.
Clinics in Sioux Falls
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5201 E 57th St, Sioux Falls, SD 57108
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6000 W 41st St Ste 100, Sioux Falls, SD 57106
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4301 W 57th St #160, Sioux Falls, SD 57108
NPI match · Verified 10/19 -
5617 S Southeastern Ave, Sioux Falls, SD 57108
Verified 10/19 -
2101 W 41st St Unit 113, Sioux Falls, SD 57105
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4908 E Rosa Parks Pl, Sioux Falls, SD 57110
NPI match · Verified 10/19 -
2001 W Trevi Pl, Sioux Falls, SD 57108
NPI match · Verified 10/19 -
5919 S Remington Pl Ste 200, Sioux Falls, SD 57108
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3800 E Vendavel St, Sioux Falls, SD 57108
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5011 S Louise Ave, Sioux Falls, SD 57108
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4900 E 57th St Ste B, Sioux Falls, SD 57108
Verified 10/19 -
2333 W 57th St Ste 102, Sioux Falls, SD 57108
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Sioux Falls, SD 57108
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7208 S Lyncrest Pl, Sioux Falls, SD 57108
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4928 E Rosa Parks Pl, Sioux Falls, SD 57110
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600 W 37th St Suite A, Sioux Falls, SD 57105
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5124 S Western Ave #4, Sioux Falls, SD 57108
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7520 S Grand Arbor Ct Ste 135, Sioux Falls, SD 57108
Verified 10/19 -
119 S Main Ave, Sioux Falls, SD 57104
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5009 S Bur Oak Pl, Sioux Falls, SD 57108
Verified 10/19
No listed clinic here matches every filter you picked. Remove a filter, or check telehealth options.
Compare clinics in Sioux Falls
Alphabetical. Virtual Care Atlas does not score or endorse clinics.
| Clinic | Services named | NPI match | Offers telehealth | Verified |
|---|---|---|---|---|
| Accelerate Wellness - Longevity Medicine Clinic | Peptides, GLP-1, HRT | — | Yes | |
| Avera Comprehensive Weight Management — 41st & Holbrook | GLP-1 | — | — | |
| Encompass Wellness & Aesthetics | Peptides, GLP-1, HRT | Yes | Yes | |
| Era Health | Peptides, GLP-1, NAD+, HRT, Sermorelin | — | — | |
| Functional Health Clinic | GLP-1 | — | — | |
| Gameday Men's Health Sioux Falls, SD | Peptides, GLP-1, NAD+, HRT, Sermorelin | Yes | Yes | |
| Hormones Gone Wild | HRT | Yes | — | |
| Limitless Male Medical Clinic | Peptides, GLP-1, NAD+, HRT, Sermorelin | — | — | |
| Liv Med Spa | Sioux Falls, SD | Peptides, GLP-1, HRT | — | Yes | |
| LIVE Hydration Spa Sioux Falls | GLP-1, NAD+, HRT | — | — | |
| Novo Aesthetics | GLP-1 | — | Yes | |
| Peakform Wellness Clinic | Peptides, GLP-1, HRT | — | Yes | |
| Prairie Roots Health | HRT | — | — | |
| Prime IV Hydration & Wellness - Sioux Falls | Peptides, GLP-1, NAD+, HRT, Sermorelin | — | Yes | |
| Radiant Health and Hormone Therapy | HRT | — | Yes | |
| Sioux Falls Secret for Weight Loss | GLP-1 | — | — | |
| The Confidence Collective | Peptides, GLP-1, NAD+ | — | — | |
| Thrive & Co. | Peptides, GLP-1, HRT, Sermorelin | — | Yes | |
| Vital Flow Infusions | GLP-1, NAD+ | — | — | |
| We Build Champions | Peptides, GLP-1, NAD+, HRT | — | — |
Sioux Falls by treatment
| Service (as listed on clinic sites) | Clinics |
|---|---|
| Semaglutide & GLP-1 in Sioux Falls | 17 |
| HRT & TRT in Sioux Falls | 14 |
| Peptide Therapy in Sioux Falls | 11 |
| NAD+ IV & Injection in Sioux Falls | 8 |
| Sermorelin in Sioux Falls | 5 |
| Offers telehealth | 9 |
6 clinics list four or more of these services: Era Health, Gameday Men's Health Sioux Falls, SD, Limitless Male Medical Clinic, Prime IV Hydration & Wellness - Sioux Falls, Thrive & Co. and 1 more.
How do I choose a clinic in Sioux Falls?
- Start from the service, not the brand. Use the filters above. In Sioux Falls, GLP-1 & medical weight loss is the most-listed service (17 of 20 clinics).
- Check who prescribes. Ask for the prescriber's name and look up their license with the South Dakota licensing board or on DocInfo. We matched 3 of 20 Sioux Falls clinics to an NPI organization record. That's an identifier, not a license.
- Ask "FDA-approved or compounded?" for every medication. If it's compounded, ask which pharmacy makes it. See compounded vs FDA-approved.
- Get costs in writing. We don't publish prices because they change and are rarely posted. Ask about consult fees, required labs, memberships and cancellation terms before you book.
- Consider telehealth. 9 Sioux Falls clinics mention virtual visits. Make sure the prescriber is licensed in South Dakota.
Full checklist: how to vet a peptide or GLP-1 clinic before booking.
Sioux Falls clinic FAQ
Which clinics in Sioux Falls offer semaglutide or GLP-1 weight loss?
17 of the 20 verified Sioux Falls clinics list medical weight loss or GLP-1 medications on their own website: Accelerate Wellness - Longevity Medicine Clinic, Avera Comprehensive Weight Management — 41st & Holbrook, Encompass Wellness & Aesthetics, Era Health, Functional Health Clinic, Gameday Men's Health Sioux Falls, SD and 11 more. Ask each whether it prescribes FDA-approved brand products, compounded versions, or both.
Where can I find peptide therapy in Sioux Falls?
11 Sioux Falls clinics name peptide therapy or specific peptides on their website: Accelerate Wellness - Longevity Medicine Clinic, Encompass Wellness & Aesthetics, Era Health, Gameday Men's Health Sioux Falls, SD, Limitless Male Medical Clinic, Liv Med Spa | Sioux Falls, SD and 5 more. Many peptides clinics promote are not FDA-approved for those uses.
Who offers NAD+ IV or injections in Sioux Falls?
8 listed Sioux Falls clinics or IV providers name NAD+ IV, drips or injections on their site: Era Health, Gameday Men's Health Sioux Falls, SD, Limitless Male Medical Clinic, LIVE Hydration Spa Sioux Falls, Prime IV Hydration & Wellness - Sioux Falls, The Confidence Collective and 2 more.
How many Sioux Falls clinics offer hormone therapy (HRT or TRT)?
14 of 20 verified clinics in Sioux Falls list hormone replacement, BHRT, testosterone therapy or pellet therapy on their website.
Can I see a Sioux Falls clinic by telehealth?
9 of the 20 Sioux Falls clinics say on their own website that they offer telehealth or virtual visits. Use the Telehealth filter above to see them. Prescribers generally need to be licensed in the state where you are during the visit.
How were these Sioux Falls clinics verified?
We found them in public Google Maps listings, then checked each against its own website on October 19, 2026. Services are listed only when the clinic's site names them. 3 of the 20 were also matched to an organization record in the federal NPI Registry. No clinic paid to be listed, and listings are alphabetical.
Data year: 2026. Virtual Care Atlas doesn’t rate or endorse clinics. Information comes from each clinic’s public website and the NPI Registry as of October 19, 2026. Services change, so confirm with the clinic. Something wrong? Request a correction.