17 Semaglutide & GLP-1 clinics in Sioux Falls, compared
We verified 17 clinics in Sioux Falls that list GLP-1 & medical weight loss on their own website (of 20 verified clinics in the city). Compare them below by the services they name, whether we matched an NPI organization record, telehealth mentions, and the verification date. Terms they use most: GLP-1, Medical weight loss, Weight loss program. Wegovy and Zepbound are FDA-approved for chronic weight management; compounded semaglutide/tirzepatide are not FDA-approved. Virtual Care Atlas does not rank or rate clinics; the table is alphabetical. As of .
Semaglutide & GLP-1 clinics in Sioux Falls
-
5201 E 57th St, Sioux Falls, SD 57108
-
6000 W 41st St Ste 100, Sioux Falls, SD 57106
-
4301 W 57th St #160, Sioux Falls, SD 57108
NPI match · Verified 10/19 -
5617 S Southeastern Ave, Sioux Falls, SD 57108
Verified 10/19 -
2101 W 41st St Unit 113, Sioux Falls, SD 57105
-
4908 E Rosa Parks Pl, Sioux Falls, SD 57110
NPI match · Verified 10/19 -
5919 S Remington Pl Ste 200, Sioux Falls, SD 57108
-
3800 E Vendavel St, Sioux Falls, SD 57108
-
5011 S Louise Ave, Sioux Falls, SD 57108
-
4900 E 57th St Ste B, Sioux Falls, SD 57108
Verified 10/19 -
2333 W 57th St Ste 102, Sioux Falls, SD 57108
-
7208 S Lyncrest Pl, Sioux Falls, SD 57108
-
600 W 37th St Suite A, Sioux Falls, SD 57105
-
5124 S Western Ave #4, Sioux Falls, SD 57108
-
7520 S Grand Arbor Ct Ste 135, Sioux Falls, SD 57108
Verified 10/19 -
119 S Main Ave, Sioux Falls, SD 57104
-
5009 S Bur Oak Pl, Sioux Falls, SD 57108
Verified 10/19
No listed clinic here matches every filter you picked. Remove a filter, or check telehealth options.
Compare GLP-1 & medical weight loss clinics in Sioux Falls
Facts we verified for each clinic. Order is alphabetical. Virtual Care Atlas does not score or endorse clinics.
| Clinic | Services named | NPI match | Offers telehealth | Verified |
|---|---|---|---|---|
| Accelerate Wellness - Longevity Medicine Clinic | GLP-1 | — | Yes | |
| Avera Comprehensive Weight Management — 41st & Holbrook | GLP-1 | — | — | |
| Encompass Wellness & Aesthetics | Medical weight loss | Yes | Yes | |
| Era Health | GLP-1, Medical weight loss | — | — | |
| Functional Health Clinic | Weight loss program | — | — | |
| Gameday Men's Health Sioux Falls, SD | GLP-1, Medical weight loss, Tirzepatide | Yes | Yes | |
| Limitless Male Medical Clinic | Semaglutide, Tirzepatide | — | — | |
| Liv Med Spa | Sioux Falls, SD | Weight loss program | — | Yes | |
| LIVE Hydration Spa Sioux Falls | GLP-1, Weight loss program | — | — | |
| Novo Aesthetics | GLP-1, Semaglutide, Weight loss program | — | Yes | |
| Peakform Wellness Clinic | Medical weight loss | — | Yes | |
| Prime IV Hydration & Wellness - Sioux Falls | Weight loss program | — | Yes | |
| Sioux Falls Secret for Weight Loss | Weight loss program | — | — | |
| The Confidence Collective | Medical weight loss | — | — | |
| Thrive & Co. | Medical weight loss | — | Yes | |
| Vital Flow Infusions | Weight loss medication | — | — | |
| We Build Champions | GLP-1 | — | — |
What these clinics call it
Terms found on the 17 clinics' own websites, by number of clinics using each.
| Term on clinic site | Clinics |
|---|---|
| GLP-1 | 7 |
| Medical weight loss | 6 |
| Weight loss program | 6 |
| Semaglutide | 2 |
| Tirzepatide | 2 |
| Weight loss medication | 1 |
Also offered by these clinics
- Peptide therapy11 of 17
- Hormone therapy (HRT / TRT)11 of 17
- NAD+ therapy8 of 17
- Sermorelin5 of 17
- Offers telehealth8 of 17
2 of 17 matched to an NPI organization record.
What should I ask a GLP-1 & medical weight loss clinic in Sioux Falls before booking?
Clinic websites rarely say who prescribes, where the medication comes from, or what it costs in total. Ask these 4 questions by phone or at the consult. Then check the prescriber's license with the South Dakota medical board or on DocInfo.
- Do you prescribe FDA-approved Wegovy or Zepbound, compounded semaglutide or tirzepatide, or both?
- If it's compounded, which pharmacy fills it?
- What does the program include (visits, labs, the medication itself), and what's the monthly cost in writing?
- What happens if the medication is no longer available, or you want to stop?
More in and around Sioux Falls
- All 20 Sioux Falls clinics
- Peptide Therapy in Sioux Falls
- NAD+ IV & Injection in Sioux Falls
- HRT & TRT in Sioux Falls
- Sermorelin in Sioux Falls
- GLP-1 weight-loss clinics in South Dakota
- GLP-1 & medical weight loss: guide & FDA status
Semaglutide & GLP-1 in Sioux Falls: FAQ
How many clinics offer GLP-1 & medical weight loss in Sioux Falls?
17 of the 20 verified clinics in Sioux Falls, SD list GLP-1 & medical weight loss on their own website as of October 19, 2026: Accelerate Wellness - Longevity Medicine Clinic, Avera Comprehensive Weight Management — 41st & Holbrook, Encompass Wellness & Aesthetics, Era Health, Functional Health Clinic, Gameday Men's Health Sioux Falls, SD, Limitless Male Medical Clinic, Liv Med Spa | Sioux Falls, SD and 9 more.
What do Sioux Falls clinics call it on their websites?
The terms we found most often were "GLP-1" (7 clinics), "Medical weight loss" (6 clinics), "Weight loss program" (6 clinics), "Semaglutide" (2 clinics), "Tirzepatide" (2 clinics). Each clinic's page shows its exact wording and the page we found it on.
Do any Sioux Falls GLP-1 & medical weight loss clinics offer telehealth?
8 of these 17 clinics mention telehealth or virtual visits on their website. The prescriber generally needs a license in South Dakota, or wherever you are during the visit.
Is GLP-1 & medical weight loss FDA-approved?
Wegovy and Zepbound are FDA-approved for chronic weight management; compounded semaglutide/tirzepatide are not FDA-approved. Our GLP-1 & medical weight loss guide links the FDA sources.
Data year 2026, verified . Virtual Care Atlas doesn’t rate or endorse clinics, and the order is alphabetical. Information comes from each clinic’s public website. Confirm services and prescriber licensing with the clinic. Request a correction.