Virtual Care Atlas

29 HRT & TRT clinics in Knoxville, compared

We verified 29 clinics in Knoxville that list hormone therapy on their own website (of 36 verified clinics in the city). Compare them below by the services they name, whether we matched an NPI organization record, telehealth mentions, and the verification date. Terms they use most: Bioidentical hormones, Hormone replacement, Hormone therapy. FDA recommends FDA-approved hormone products and says it lacks evidence that compounded “bioidentical” hormones are safer or more effective. Virtual Care Atlas does not rank or rate clinics; the table is alphabetical. As of .

Map of 29 hormone therapy clinics in Knoxville, TN Map of 29 hormone therapy clinics in Knoxville, TN
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HRT & TRT clinics in Knoxville

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29 of 29 HRT & TRT clinics in Knoxville

  1. Anti-Aging Medical Spa, Inc

    6714 Central Ave Pike # E, Knoxville, TN 37912

    • HRT
    (865) 688-7205 Website for Anti-Aging Medical Spa, Inc (opens in new tab)
    Verified 10/19

  2. Be The New You Weight Loss

    9080 Barbee Ln #105, Knoxville, TN 37923

    • GLP-1
    • HRT
    Website for Be The New You Weight Loss (opens in new tab)
    Verified 10/19

  3. Drip into Wellness

    Knoxville, TN 37919

    • NAD+
    • HRT
    (865) 214-6064 Website for Drip into Wellness (opens in new tab)
    Verified 10/19

  4. Hydr865 : IV Infusion Therapy & Weight Loss

    2453 University Commons Way, Knoxville, TN 37919

    • GLP-1
    • HRT
    (865) 398-4361 Website for Hydr865 : IV Infusion Therapy & Weight Loss (opens in new tab)
    Verified 10/19

  5. Integrity Medical - Direct Primary Care

    4629 Mill Branch Ln, Knoxville, TN 37938

    • HRT
    (865) 201-1756 Website for Integrity Medical - Direct Primary Care (opens in new tab)
    Verified 10/19

  6. Knox Wellness

    9320 Kingston Pike, Knoxville, TN 37922

    • HRT
    (865) 801-9501 Website for Knox Wellness (opens in new tab)
    NPI match · Verified 10/19

  7. Knoxville Weight Loss and Wellness

    215 Center Park Dr, Knoxville, TN 37922

    • Peptides
    • GLP-1
    • HRT
    • Offers telehealth
    (865) 671-1313 Website for Knoxville Weight Loss and Wellness (opens in new tab)
    Verified 10/19

  8. Lifespring Health Center

    Knoxville, TN 37918

    • GLP-1
    • HRT
    • Offers telehealth
    (865) 229-4259 Website for Lifespring Health Center (opens in new tab)
    Verified 10/19

  9. Low T Center Knoxville | Hormone Health & TRT Clinic

    11039 Parkside Dr, Knoxville, TN 37934

    • Peptides
    • GLP-1
    • HRT
    • Sermorelin
    • Offers telehealth
    Website for Low T Center Knoxville | Hormone Health & TRT Clinic (opens in new tab)
    NPI match · Verified 10/19

  10. MC Wellness and Aesthetics

    1750 Commons Point Dr Ste 102, Knoxville, TN 37932

    • Peptides
    • GLP-1
    • NAD+
    • HRT
    (865) 353-4093 Website for MC Wellness and Aesthetics (opens in new tab)
    Verified 10/19

  11. Old City Medspa

    104 W Summit Hill Dr SW, Knoxville, TN 37902

    • GLP-1
    • HRT
    (865) 247-5057 Website for Old City Medspa (opens in new tab)
    Verified 10/19

  12. Optimal Health - Kingston Pike

    8906 Kingston Pike, Knoxville, TN 37923

    • Peptides
    • GLP-1
    • HRT
    (865) 290-7997 Website for Optimal Health - Kingston Pike (opens in new tab)
    NPI match · Verified 10/19

  13. Optimize U- Knoxville

    150 Lovell Rd #107, Knoxville, TN 37934

    • Peptides
    • GLP-1
    • HRT
    • Offers telehealth
    (865) 766-2796 Website for Optimize U- Knoxville (opens in new tab)
    Verified 10/19

  14. Performance Medicine (112 Hotel Rd)

    112 Hotel Rd, Knoxville, TN 37918

    • GLP-1
    • HRT
    • Offers telehealth
    (865) 381-7322 Website for Performance Medicine (112 Hotel Rd) (opens in new tab)
    Verified 10/19

  15. Performance Medicine (9949 Kingston Pike)

    9949 Kingston Pike, Knoxville, TN 37922

    • GLP-1
    • HRT
    • Offers telehealth
    (865) 249-7672 Website for Performance Medicine (9949 Kingston Pike) (opens in new tab)
    Verified 10/19

  16. Prime IV Hydration & Wellness - Knoxville

    4409 Kingston Pike, Knoxville, TN 37919

    • Peptides
    • GLP-1
    • NAD+
    • HRT
    • Sermorelin
    • Offers telehealth
    (865) 302-3182 Website for Prime IV Hydration & Wellness - Knoxville (opens in new tab)
    Verified 10/19

  17. RevitalyzeMD

    6504 Deane Hill Dr, Knoxville, TN 37919

    • Peptides
    • GLP-1
    • NAD+
    • HRT
    • Offers telehealth
    (865) 294-9800 Website for RevitalyzeMD (opens in new tab)
    Verified 10/19

  18. Slim Down Wellness

    9700 Kingston Pike #17, Knoxville, TN 37922

    • GLP-1
    • NAD+
    • HRT
    (865) 909-7546 Website for Slim Down Wellness (opens in new tab)
    Verified 10/19

  19. Smiley Aesthetics Medical Spa

    525 Union Ave, Knoxville, TN 37902

    • Peptides
    • GLP-1
    • NAD+
    • HRT
    • Sermorelin
    • Offers telehealth
    (865) 350-6187 Website for Smiley Aesthetics Medical Spa (opens in new tab)
    Verified 10/19

  20. Terrain Wellness

    413 Montbrook Ln, Knoxville, TN 37919

    • HRT
    • Offers telehealth
    (865) 281-1901 Website for Terrain Wellness (opens in new tab)
    Verified 10/19

  21. The Wellness Room

    151 Sherway Rd #1, Knoxville, TN 37922

    • HRT
    (865) 274-0199 Website for The Wellness Room (opens in new tab)
    Verified 10/19

  22. Timeline Health

    900 E Hill Ave Ste 205, Knoxville, TN 37915

    • GLP-1
    • HRT
    • Offers telehealth
    (865) 333-3083 Website for Timeline Health (opens in new tab)
    Verified 10/19

  23. Vital Hydration

    10932 Murdock Dr #102b, Knoxville, TN 37932

    • Peptides
    • GLP-1
    • NAD+
    • HRT
    (865) 282-4634 Website for Vital Hydration (opens in new tab)
    Verified 10/19

  24. Weigh To Go Weight Loss Center (1424, 6714 Central Ave Pike F)

    Knoxville, TN 37912

    • Peptides
    • GLP-1
    • NAD+
    • HRT
    (865) 219-8650 Website for Weigh To Go Weight Loss Center (1424, 6714 Central Ave Pike F) (opens in new tab)
    Verified 10/19

  25. Weigh To Go Weight Loss Center (461 Park 40 N Blvd)

    Knoxville, TN 37923

    • Peptides
    • GLP-1
    • NAD+
    • HRT
    (865) 851-8876 Website for Weigh To Go Weight Loss Center (461 Park 40 N Blvd) (opens in new tab)
    Verified 10/19

  26. Wellness from Within

    11653 Parkside Dr, Knoxville, TN 37934

    • GLP-1
    • HRT
    (865) 603-3000 Website for Wellness from Within (opens in new tab)
    Verified 10/19

  27. West Knox Wellness

    408 Erin Dr Ste 8, Knoxville, TN 37919

    • Peptides
    • GLP-1
    • HRT
    (865) 338-1372 Website for West Knox Wellness (opens in new tab)
    Verified 10/19

  28. West Side Wellness

    9217 Park West Blvd Ste C-2, Knoxville, TN 37923

    • GLP-1
    • HRT
    (865) 862-4575 Website for West Side Wellness (opens in new tab)
    Verified 10/19

  29. Zero Gravity Medical

    Knoxville, TN 37922

    • GLP-1
    • HRT
    • Offers telehealth
    (865) 236-1811 Website for Zero Gravity Medical (opens in new tab)
    NPI match · Verified 10/19

Compare hormone therapy clinics in Knoxville

Facts we verified for each clinic. Order is alphabetical. Virtual Care Atlas does not score or endorse clinics.

Comparison of 29 hormone therapy clinics in Knoxville
Clinic Services named NPI match Offers telehealth Verified
Anti-Aging Medical Spa, Inc BHRT, Bioidentical hormones — —
Be The New You Weight Loss Hormone therapy — —
Drip into Wellness HRT, TRT — —
Hydr865 : IV Infusion Therapy & Weight Loss HRT, TRT — —
Integrity Medical - Direct Primary Care Hormone replacement, Hormone therapy — —
Knox Wellness BHRT, Bioidentical hormones Yes —
Knoxville Weight Loss and Wellness Hormone replacement, HRT — Yes
Lifespring Health Center Bioidentical hormones, Testosterone therapy — Yes
Low T Center Knoxville | Hormone Health & TRT Clinic Testosterone replacement, TRT Yes Yes
MC Wellness and Aesthetics Hormone optimization, Hormone therapy — —
Old City Medspa TRT — —
Optimal Health - Kingston Pike Hormone replacement Yes —
Optimize U- Knoxville Hormone therapy — Yes
Performance Medicine (112 Hotel Rd) Bioidentical hormones, Hormone therapy — Yes
Performance Medicine (9949 Kingston Pike) BHRT, Hormone therapy, Testosterone therapy — Yes
Prime IV Hydration & Wellness - Knoxville Bioidentical hormones — Yes
RevitalyzeMD HRT — Yes
Slim Down Wellness Hormone replacement — —
Smiley Aesthetics Medical Spa Bioidentical hormones, Hormone replacement — Yes
Terrain Wellness Bioidentical hormones, Hormone optimization, Hormone replacement — Yes
The Wellness Room Hormone replacement — —
Timeline Health BHRT, Bioidentical hormones, Hormone optimization — Yes
Vital Hydration TRT — —
Weigh To Go Weight Loss Center (1424, 6714 Central Ave Pike F) Bioidentical hormones, Hormone replacement, Hormone therapy — —
Weigh To Go Weight Loss Center (461 Park 40 N Blvd) Bioidentical hormones, Hormone replacement, Hormone therapy — —
Wellness from Within HRT — —
West Knox Wellness HRT — —
West Side Wellness Bioidentical hormones — —
Zero Gravity Medical Testosterone replacement, TRT Yes Yes

What these clinics call it

Terms found on the 29 clinics' own websites, by number of clinics using each.

Service terms used by Knoxville hormone therapy clinics
Term on clinic siteClinics
Bioidentical hormones11
Hormone replacement9
Hormone therapy8
HRT6
TRT6
BHRT4
Hormone optimization3
Testosterone replacement2
Testosterone therapy2

Also offered by these clinics

4 of 29 matched to an NPI organization record.

What should I ask a hormone therapy clinic in Knoxville before booking?

Clinic websites rarely say who prescribes, where the medication comes from, or what it costs in total. Ask these 4 questions by phone or at the consult. Then check the prescriber's license with the Tennessee medical board or on DocInfo.

  1. Do you prescribe FDA-approved hormone products, compounded bioidentical hormones, or pellets?
  2. What baseline and follow-up labs are required, and how often?
  3. Who is the prescriber, and what is their state license number?
  4. What's the full cost: consult, labs, medication and any membership?

More in and around Knoxville

HRT & TRT in Knoxville: FAQ

How many clinics offer hormone therapy in Knoxville?

29 of the 36 verified clinics in Knoxville, TN list hormone therapy on their own website as of October 19, 2026: Anti-Aging Medical Spa, Inc, Be The New You Weight Loss, Drip into Wellness, Hydr865 : IV Infusion Therapy & Weight Loss, Integrity Medical - Direct Primary Care, Knox Wellness, Knoxville Weight Loss and Wellness, Lifespring Health Center and 21 more.

What do Knoxville clinics call it on their websites?

The terms we found most often were "Bioidentical hormones" (11 clinics), "Hormone replacement" (9 clinics), "Hormone therapy" (8 clinics), "HRT" (6 clinics), "TRT" (6 clinics). Each clinic's page shows its exact wording and the page we found it on.

Do any Knoxville hormone therapy clinics offer telehealth?

12 of these 29 clinics mention telehealth or virtual visits on their website. The prescriber generally needs a license in Tennessee, or wherever you are during the visit.

Is hormone therapy FDA-approved?

FDA recommends FDA-approved hormone products and says it lacks evidence that compounded “bioidentical” hormones are safer or more effective. Our Hormone therapy (HRT / TRT) guide links the FDA sources.

Data year 2026, verified . Virtual Care Atlas doesn’t rate or endorse clinics, and the order is alphabetical. Information comes from each clinic’s public website. Confirm services and prescriber licensing with the clinic. Request a correction.