Knoxville, Tennessee · listing
Smiley Aesthetics Medical Spa
Smiley Aesthetics Medical Spa is a clinic in Knoxville, TN whose own website lists peptide therapy, GLP-1 weight loss, NAD+ therapy, hormone therapy and sermorelin and mentions telehealth. We checked its website on . Virtual Care Atlas doesn’t rate clinics. Confirm services, prices and the prescriber’s license with the clinic before booking.
Verified facts
- Address
- 525 Union Ave
Knoxville, TN 37902 Confirmed on clinic site - Phone
- (865) 350-6187 Confirmed on clinic site
- Website
- smileyaesthetics.com 7 pages checked
- Offers telehealth
- Yes, per its website (smileyaesthetics.com/locations/knoxville). It also has the in-person location above.
- NPI (organization)
- No organization match found. Many practices bill under individual clinicians.
- Last verified
Services listed on their website
We tag a service only when smileyaesthetics.com names it, either repeatedly or on a dedicated page. Here are the terms we found and where. This is what the clinic says it offers, not our endorsement.
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Peptide therapy
Terms found: CJC-1295 · Ipamorelin
Source: smileyaesthetics.com/telehealth-visits
Many peptides clinics offer are not FDA-approved; FDA lists several (e.g. BPC-157, CJC-1295, ipamorelin) as bulk substances that may present significant safety risks in compounding. More on peptide therapy and FDA status
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GLP-1 & medical weight loss
Terms found: GLP-1 · Medical weight loss · Weight loss program
Source: smileyaesthetics.com/locations/knoxville
Wegovy and Zepbound are FDA-approved for chronic weight management; compounded semaglutide/tirzepatide are not FDA-approved. More on GLP-1 & medical weight loss and FDA status
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NAD+ therapy
Terms found: NAD+
Source: smileyaesthetics.com/telehealth-visits
We are not aware of an FDA-approved NAD+ infusion product for wellness uses; clinic preparations are generally compounded. More on NAD+ therapy and FDA status
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Hormone therapy (HRT / TRT)
Terms found: Bioidentical hormones · Hormone replacement
Source: smileyaesthetics.com/locations/knoxville
FDA recommends FDA-approved hormone products and says it lacks evidence that compounded “bioidentical” hormones are safer or more effective. More on hormone therapy and FDA status
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Sermorelin
Terms found: Sermorelin
Source: smileyaesthetics.com/telehealth-visits
Branded sermorelin (Geref) was discontinued in 2008; clinic sermorelin today is generally compounded. More on sermorelin and FDA status
Other listed clinics nearby
All 36 in KnoxvilleSorted by straight-line distance from Smiley Aesthetics Medical Spa: Old City Medspa 0.3 mi · Timeline Health 0.9 mi · Hydr865 : IV Infusion Therapy & Weight Loss 1.4 mi · Prime IV Hydration & Wellness 3.5 mi · Knoxville Weight Loss Clinic 4.2 mi · Lifespring Health Center 4.5 mi.
Smiley Aesthetics Medical Spa: common questions
What services does Smiley Aesthetics Medical Spa list?
As of October 19, 2026, Smiley Aesthetics Medical Spa's own website lists peptide therapy, GLP-1 weight loss, NAD+ therapy, hormone therapy and sermorelin. Peptide therapy: we found "CJC-1295", "Ipamorelin". GLP-1 & medical weight loss: we found "GLP-1", "Medical weight loss", "Weight loss program". NAD+ therapy: we found "NAD+". Hormone therapy (HRT / TRT): we found "Bioidentical hormones", "Hormone replacement". Sermorelin: we found "Sermorelin". Services change, so confirm with the clinic.
Does Smiley Aesthetics Medical Spa offer semaglutide or tirzepatide?
Its website lists medical weight loss / GLP-1 services but did not name semaglutide or tirzepatide on the pages we checked. Ask the clinic which medications it prescribes.
Does Smiley Aesthetics Medical Spa offer telehealth?
Yes. Its website mentions telehealth or virtual visits. Prescribers generally need to be licensed in the state where you are during the visit.
Where is Smiley Aesthetics Medical Spa located?
525 Union Ave, Knoxville, TN 37902. The nearest other listed clinic is Old City Medspa, about 0.3 miles away.
Is Smiley Aesthetics Medical Spa in the NPI Registry?
We did not find a matching organization record. Many practices bill under individual clinicians' NPIs instead. You can search the NPI Registry yourself by clinician name.
Virtual Care Atlas is an independent directory. We don’t rate, review or endorse clinics, and this listing isn’t medical advice. Confirm services, licensing and prices directly with the clinic, and check the prescriber’s license with your state board.